US 11,986,294 B2
Method, system and computer program product for CGM-based prevention of hypoglycemia via hypoglycemia risk assessment and smooth reduction insulin delivery
Boris P. Kovatchev, Charlottesville, VA (US); Marc D. Breton, Charlottesville, VA (US); and Stephen D. Patek, Charlottesville, VA (US)
Assigned to UNIVERSITY OF VIRGINIA PATENT FOUNDATION, Charlottesville, VA (US)
Filed by UNIVERSITY OF VIRGINIA PATENT FOUNDATION, Charlottesville, VA (US)
Filed on May 30, 2023, as Appl. No. 18/325,564.
Application 17/070,245 is a division of application No. 15/669,111, filed on Aug. 4, 2017, granted, now 10,842,419, issued on Nov. 24, 2020.
Application 18/325,564 is a continuation of application No. 17/070,245, filed on Oct. 14, 2020, granted, now 11,723,562.
Application 15/669,111 is a continuation of application No. 14/015,831, filed on Aug. 30, 2013, granted, now 9,750,438, issued on Sep. 5, 2017.
Application 14/015,831 is a continuation of application No. 13/203,469, granted, now 8,562,587, issued on Oct. 22, 2013, previously published as PCT/US2010/025405, filed on Feb. 25, 2010.
Claims priority of provisional application 61/263,932, filed on Nov. 24, 2009.
Claims priority of provisional application 61/182,485, filed on May 29, 2009.
Claims priority of provisional application 61/155,357, filed on Feb. 25, 2009.
Prior Publication US 2023/0293062 A1, Sep. 21, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/145 (2006.01); A61B 5/00 (2006.01); A61M 5/172 (2006.01); G16H 20/17 (2018.01); G16H 40/63 (2018.01); G16H 50/50 (2018.01); G16H 40/67 (2018.01)
CPC A61B 5/14532 (2013.01) [A61B 5/0002 (2013.01); A61B 5/0004 (2013.01); A61B 5/4839 (2013.01); A61B 5/7275 (2013.01); A61B 5/746 (2013.01); A61M 5/1723 (2013.01); G16H 20/17 (2018.01); G16H 40/63 (2018.01); G16H 50/50 (2018.01); G16H 40/67 (2018.01)] 28 Claims
OG exemplary drawing
 
1. Non-transient computer-readable media comprising instructions for causing a computing environment to perform a method, the method for preventing or mitigating hypoglycemia in a patient, the instructions comprising:
receiving, from sensor electronics of a glucose monitor, data related to a glucose concentration;
assessing a risk of hypoglycemia based on at least the data related to the glucose concentration;
evaluating the assessed risk of hypoglycemia, and
outputting to an output device a result of said evaluation, wherein the result includes a recommendation signal or a control signal related to attenuation of insulin delivery when the evaluating indicates that the assessed risk of hypoglycemia has passed or is predicted to pass a threshold;
wherein the recommendation signal or the control signal related to attenuation of insulin delivery is generated by multiplying a basal rate by an attenuation factor.