US 11,655,437 B2
Delivery systems for peroxide compounds and their applications
Christian Guy Becker, King of Prussia, PA (US); and Pan Pan, King of Prussia, PA (US)
Assigned to Arkema Inc., King of Prussia, PA (US)
Appl. No. 16/651,403
Filed by Arkema Inc., King of Prussia, PA (US)
PCT Filed Sep. 14, 2018, PCT No. PCT/US2018/051017
§ 371(c)(1), (2) Date Mar. 27, 2020,
PCT Pub. No. WO2019/067232, PCT Pub. Date Apr. 4, 2019.
Claims priority of provisional application 62/564,311, filed on Sep. 28, 2017.
Prior Publication US 2020/0299621 A1, Sep. 24, 2020
Int. Cl. C11D 11/00 (2006.01); C11D 3/39 (2006.01); C11D 7/10 (2006.01); C11D 7/12 (2006.01); C11D 7/20 (2006.01); C11D 7/26 (2006.01); C11D 17/00 (2006.01); A61K 8/22 (2006.01); A61K 8/25 (2006.01); A61Q 11/00 (2006.01); A61Q 11/02 (2006.01); A61Q 17/00 (2006.01); A61Q 5/08 (2006.01); C11D 7/08 (2006.01)
CPC C11D 11/0088 (2013.01) [A61K 8/22 (2013.01); A61K 8/25 (2013.01); A61Q 5/08 (2013.01); A61Q 11/00 (2013.01); A61Q 11/02 (2013.01); A61Q 17/005 (2013.01); C11D 3/3947 (2013.01); C11D 7/08 (2013.01); C11D 7/10 (2013.01); C11D 7/12 (2013.01); C11D 7/20 (2013.01); C11D 7/26 (2013.01); C11D 11/0017 (2013.01); C11D 17/0034 (2013.01); A61K 2800/10 (2013.01)] 35 Claims
 
1. A delivery system for at least one peroxide compound comprising:
a) a hydrophilic inorganic solid support selected from the group consisting of precipitated silica, fumed silica and mixtures thereof, wherein the hydrophilic inorganic solid support is inert to the at least one peroxide compound and is capable of adsorbing a liquid while remaining dry to the touch; and
b) the at least one peroxide compound, wherein the at least one peroxide compound is a liquid peroxide or is in a liquid solution and is capable of being adsorbed by the hydrophilic inorganic solid support;
whereby the at least one peroxide compound is adsorbed by the hydrophilic inorganic solid support while the hydrophilic inorganic solid support remains dry to the touch, thereby forming a dry to the touch delivery system for the at least one peroxide compound; wherein the delivery system comprises at least one stabilizer for the at least one peroxide compound; and
wherein the at least one peroxide compound has an initial active oxygen content and wherein the at least one peroxide compound retains at least 80% of the initial active oxygen content after storage for 1 week at 50° C.