US 11,655,274 B2
Glycosylated YghJ polypeptides from enterotoxigenic Escherichia coli (ETEC)
Anders Boysen, Odense SØ (DK); Jakob Møller-Jensen, Odense M (DK); Giuseppe Palmisano, Turi (IT); and Martin Røssel Larsen, Odense S (DK)
Assigned to Aarhus Universitet, Aarhus C (DK); and Syddansk Universitet, Odense M (DK)
Filed by Syddansk Universitet, Odense M (DK); and Aarhus Universitet, Aarhus C (DK)
Filed on Jun. 12, 2020, as Appl. No. 16/900,799.
Application 16/900,799 is a continuation of application No. 15/766,209, abandoned, previously published as PCT/DK2016/050321, filed on Oct. 6, 2016.
Claims priority of application No. 15188608 (EP), filed on Oct. 6, 2015.
Prior Publication US 2021/0115095 A1, Apr. 22, 2021
Int. Cl. C07K 14/245 (2006.01); A61K 39/108 (2006.01)
CPC C07K 14/245 (2013.01) [A61K 39/0258 (2013.01); Y02A 50/30 (2018.01)] 16 Claims
1. A pharmaceutical composition comprising:
an O-linked glycosylated polypeptide fragment that is 13 to 42 amino acid-residues long, wherein the O-linked glycosylated polypeptide fragment comprises at least 90% sequence identity to a sequence selected form the group consisting of SEQ ID NO: 7, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 25, SEQ ID NO: 26, SEQ ID NO: 15, SEQ ID NO: 28, SEQ ID NO: 32, SEQ ID NO: 44 and SEQ ID NO: 46.