US 11,654,410 B2
Method for preparing biodegradable microcapsules and microcapsules thus obtained
Yves Ortais, Gemenos (FR); Thierry Ribeiro, La Fare les Oliviers (FR); Kaouthar Oudoua, Marseilles (FR); The Hien Ho, Marseilles (FR); Didier Gigmes, Allauch (FR); Catherine Guillaneuf, Marseilles (FR); and Yohann Guillaneuf, Marseilles (FR)
Assigned to GEM INNOV, Gemenos (FR)
Filed by GEM INNOV, Gemenos (FR); UNIVERSITÉ D'AIX MARSEILLE, Marseilles (FR); and CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris (FR)
Filed on May 16, 2020, as Appl. No. 16/876,006.
Claims priority of provisional application 62/927,622, filed on Oct. 29, 2019.
Claims priority of application No. 1905127 (FR), filed on May 16, 2019; and application No. 1912148 (FR), filed on Oct. 29, 2019.
Prior Publication US 2020/0360889 A1, Nov. 19, 2020
Int. Cl. B01J 13/16 (2006.01); C08F 220/34 (2006.01); B01J 13/22 (2006.01); C08G 73/02 (2006.01); C08L 77/06 (2006.01); C09D 101/02 (2006.01)
CPC B01J 13/16 (2013.01) [B01J 13/22 (2013.01); C08F 220/34 (2013.01); C08G 73/02 (2013.01); C08L 77/06 (2013.01); C08G 2230/00 (2013.01); C08L 2201/06 (2013.01); C09D 101/02 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A method for manufacturing microcapsules containing an active substance, the method comprising:
providing an aqueous solution of a surfactant, an oily phase comprising said active substance and a first monomer, and a polar phase comprising a second monomer;
preparing an oil-in-water emulsion by adding said oily phase to said aqueous solution of the surfactant;
adding said polar phase to said oil-in-water emulsion to obtain a polymer by polymerization of said first monomer and said second monomer in a reaction mixture; and
isolating said microcapsules, including a wall formed by said polymer and containing said active substance, from the reaction mixture;
wherein said polymer is a poly(beta-amino ester).