US 11,654,281 B2
Neural stimulation device
Mohammed Abouelsoud, Mayfield Heights, OH (US)
Assigned to U, LLC, Columbus, OH (US)
Filed by U, LLC, Mayfied Heights, OH (US)
Filed on Jun. 1, 2021, as Appl. No. 17/336,224.
Claims priority of provisional application 63/032,332, filed on May 29, 2020.
Prior Publication US 2021/0370063 A1, Dec. 2, 2021
Int. Cl. A61N 1/36 (2006.01); A61N 1/04 (2006.01)
CPC A61N 1/36025 (2013.01) [A61N 1/0456 (2013.01); A61N 1/0476 (2013.01); A61N 1/36031 (2017.08); A61N 1/36034 (2017.08)] 20 Claims
OG exemplary drawing
 
1. A neurostimulation device comprising:
a plurality of electrodes configured to be placed around at least a portion of a patient head such that each electrode has a plurality of electrical paths through the brain of the patient to at least a subset of the other electrodes; and
a controller configured to selectively control current between sets of opposing electrodes through the patient brain to selectively stimulate a region of interest of the patient brain during a period of time that is less than a neuronal time integrity constant by
providing a first set of electrical current pulses to a first set of opposing electrodes to create a first electric field gradient across the patient brain, and
providing a plurality of additional sets of electrical current pulses to additional sets of opposing electrodes, each offset from the first set of electrodes, to create a plurality of non-uniform electric field gradients across the brain, each partially overlapping with the first electric field gradient, at least one non-uniform electric field gradient having an opposite polarity to the first electric field gradient,
wherein the non-uniform electric field gradients at least partially negate the first electric field gradient such that a first net potential is created in the region of interest in the patient brain that exceeds a predetermined neuron stimulation threshold and a second net potential is created in areas of the patient brain outside the region of interest that is less that the neuron stimulation threshold.