US 11,654,195 B2
Eco-friendly smart photosensitizer and photo-stem cell therapy product comprising same
Jin Wang Kim, Seoul (KR); Jung Ok Lee, Seoul (KR); Hyun Ji Kim, Seoul (KR); and Hyun Woo Kim, Seoul (KR)
Appl. No. 17/786,980
Filed by Jin Wang Kim, Seoul (KR); Jung Ok Lee, Seoul (KR); Hyun Ji Kim, Seoul (KR); and Hyun Woo Kim, Seoul (KR)
PCT Filed Nov. 26, 2020, PCT No. PCT/KR2020/017009
§ 371(c)(1), (2) Date Jun. 17, 2022,
PCT Pub. No. WO2021/125611, PCT Pub. Date Jun. 24, 2021.
Claims priority of application No. 10-2019-0171174 (KR), filed on Dec. 19, 2019; and application No. 10-2020-0101343 (KR), filed on Aug. 12, 2020.
Prior Publication US 2023/0088872 A1, Mar. 23, 2023
Int. Cl. A61K 47/00 (2006.01); A61P 35/00 (2006.01); A61K 41/00 (2020.01); A61K 47/69 (2017.01); A61K 47/61 (2017.01)
CPC A61K 41/0057 (2013.01) [A61K 47/61 (2017.08); A61K 47/6939 (2017.08); A61P 35/00 (2018.01)] 7 Claims
 
1. A photosensitizer, comprising:
a conjugate of hydroxypropyl methylcellulose and a porfimer sodium photosensitizer,
wherein the hydroxypropyl methylcellulose is represented by Formula 2 below,
the porfimer sodium photosensitizer is represented by Formula 3 below, and
the hydroxypropyl methylcellulose and the porfimer sodium photosensitizer form a conjugate by an ester bond:

OG Complex Work Unit Chemistry
In Formula 2,
n is an integer from 0 to 7

OG Complex Work Unit Chemistry
In Formula 3,
R is each independently —CH═CH2 or —CH(OH)—CH3, and
n is an integer from 0 to 6.