US 11,654,012 B2
Connective tissue to bone interface scaffolds
Dushyanth R. Surakanti, Madison, NJ (US); Adam B. Yanke, Madison, NJ (US); Adam W. Martinez, Madison, NJ (US); Kurt W. S. Klitzke, Madison, NJ (US); Travis E. Entrop, Madison, NJ (US); Dimitrios J. Angelis, Madison, NJ (US); Eric A. Nauman, West Lafayette, IN (US); and Darryl A. Dickerson, Miami, FL (US)
Assigned to Sparta Biopharma Inc., Madison, NJ (US)
Filed by Sparta Biopharma Inc., Madison, NJ (US)
Filed on Apr. 5, 2021, as Appl. No. 17/222,719.
Application 17/222,719 is a continuation of application No. 17/015,043, filed on Sep. 8, 2020, granted, now 10,966,816.
Claims priority of provisional application 63/069,658, filed on Aug. 24, 2020.
Claims priority of provisional application 62/923,470, filed on Oct. 18, 2019.
Prior Publication US 2021/0220116 A1, Jul. 22, 2021
Int. Cl. A61F 2/08 (2006.01); A61L 27/36 (2006.01); A61F 2/28 (2006.01); A61F 2/30 (2006.01)
CPC A61F 2/0811 (2013.01) [A61F 2/2846 (2013.01); A61L 27/3604 (2013.01); A61L 27/3608 (2013.01); A61F 2002/0823 (2013.01); A61F 2002/0876 (2013.01); A61F 2002/2835 (2013.01); A61F 2002/30059 (2013.01); A61F 2002/30448 (2013.01); A61F 2210/0076 (2013.01); A61F 2220/005 (2013.01); A61F 2220/0075 (2013.01); A61F 2250/006 (2013.01)] 22 Claims
OG exemplary drawing
1. A method of repairing an enthesis, the method comprising:
removing a region of a cortical layer of a bone to expose a marrow material in an attachment region;
anchoring one or more suture to the bone;
securing a graft that is flexible, compressible and compliant to the attachment region, the graft having a length, a width and a thickness, wherein the thickness is less than half the length and half the width, the graft further comprising: a first layer of demineralized bone and a second layer of mineralized bone that is continuously adjacent to the first layer, wherein the second layer has a thickness that is less than 1.5 mm, further wherein securing the graft to the attachment region comprises securing the second layer of the graft in contact with the marrow material, wherein the second layer compliantly conforms to the attachment region; and
suturing a tendon against the first layer using the one or more sutures.