US 11,653,929 B2
Embolization catheter with integral filter
Michael Gabriel Tal, Savyon (IL); Eran Miller, Moshav Beit Elazari (IL); Nir Holzman, Rishon LeZion (IL); Osnat Harbater, Raanana (IL); and Yuval Zipory, Modiin (IL)
Assigned to ACCURATE MEDICAL THERAPEUTICS LTD., Rehovot (unknown)
Appl. No. 16/761,051
PCT Filed Nov. 1, 2018, PCT No. PCT/IL2018/051165
§ 371(c)(1), (2) Date May 1, 2020,
PCT Pub. No. WO2019/087191, PCT Pub. Date May 9, 2019.
Claims priority of provisional application 62/580,513, filed on Nov. 2, 2017.
Prior Publication US 2021/0177430 A1, Jun. 17, 2021
Int. Cl. A61B 17/12 (2006.01); A61L 29/04 (2006.01); A61L 29/08 (2006.01); A61M 25/00 (2006.01)
CPC A61B 17/12186 (2013.01) [A61L 29/049 (2013.01); A61L 29/085 (2013.01); A61M 25/005 (2013.01); A61M 25/007 (2013.01); A61M 25/0021 (2013.01); A61B 2017/1205 (2013.01); A61M 2025/0042 (2013.01); A61M 2025/0046 (2013.01)] 15 Claims
OG exemplary drawing
1. An embolization microcatheter for delivery of embolization particles to a target area, the microcatheter comprising:
a first section located at a proximal end of the microcatheter and configured for delivering the microcatheter to a target location;
a second section located at a distal end of the microcatheter and configured to restrict flow through the second section; the second section comprising a distal end opening sized and shaped to allow delivery of a suspension flowing through the microcatheter, the suspension comprising a suspension fluid and the embolization particles; and
a third section located between the first and the second sections; the third section comprising:
a skeleton formed of braided or coiled wires;
a polymeric layer, an outer surface and an inner surface; the polymeric layer intercalated into and/or overlaying the skeleton;
a plurality of axial slits formed proximal to and at a predetermined distance from the distal end opening, wherein each of the plurality of axial slits has a smallest cross-sectional dimension configured to prevent outflow of the embolization particles through each of the plurality of axial slits while allowing outflow of the suspension fluid through each of the plurality of axial slits, and wherein each of the plurality of axial slits extends from the outer surface of the third section to the inner surface of the third section, and wherein each of the plurality of slits has a larger width at the outer surface as compared to at the inner surface; and
wherein the plurality of slits are sized and shaped to allow a flow of the particles downstream of the third section at a volume flow rate which allows delivery of essentially all particles in the suspension through the distal end opening while preventing their backflow;
wherein each axial slit of the plurality of slits is spaced apart by 200-400 microns;
wherein the polymeric layer has an ultimate tensile strength of 2000-10000 psi and an ultimate elongation of 350-450%, and a Shore hardness of about 80A-90A;
wherein the third section is formed of a material having larger flexibility than the first section; wherein the embolization microcatheter has a tensile strength of at least about 5N, and wherein the third section has a kink-free radius of 0.5 mm-1.5 mm, while distortion of the axial slits is hindered.