US 12,306,120 B2
Apparatus and method for biological analyte studying using x-ray fluorescence
Peiyan Cao, Shenzhen (CN); and Yurun Liu, Shenzhen (CN)
Assigned to SHENZHEN XPECTVISION TECHNOLOGY CO., LTD., Shenzhen (CN)
Filed by SHENZHEN XPECTVISION TECHNOLOGY CO., LTD., Shenzhen (CN)
Filed on May 11, 2023, as Appl. No. 18/195,984.
Application 18/195,984 is a continuation of application No. PCT/CN2020/131468, filed on Nov. 25, 2020.
Prior Publication US 2023/0280292 A1, Sep. 7, 2023
Int. Cl. G01N 23/223 (2006.01); G01N 33/58 (2006.01)
CPC G01N 23/223 (2013.01) [G01N 33/582 (2013.01); G01N 2223/612 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An apparatus, comprising:
an X-ray source;
an X-ray detector;
wherein the X-ray source is configured to direct an X-ray beam toward a surface at a glancing angle at which the X-ray beam undergoes total external reflection by the surface;
wherein a first biological analyte is immobilized to the surface and a first element is attached to the first biological analyte;
wherein the X-ray beam is capable of causing emission of characteristic X-rays of the first element;
wherein the X-ray detector is configured to receive the characteristic X-rays of the first element but not the X-ray beam reflected by the surface;
wherein the X-ray beam directed to the surface is a fan beam.