US 12,305,215 B2
Microbiomes and methods for producing medium-chain fatty acids from organic substrates
Timothy James Donohue, Middleton, WI (US); Matthew Scarborough, Madison, WI (US); and Daniel Noguera, Madison, WI (US)
Assigned to Wisconsin Alumni Research Foundation, Madison, WI (US)
Filed by WISCONSIN ALUMNI RESEARCH FOUNDATION, Madison, WI (US)
Filed on Jan. 7, 2022, as Appl. No. 17/571,209.
Application 17/571,209 is a continuation of application No. 16/433,639, filed on Jun. 6, 2019, granted, now 11,242,544.
Claims priority of provisional application 62/846,378, filed on May 10, 2019.
Claims priority of provisional application 62/697,249, filed on Jul. 12, 2018.
Claims priority of provisional application 62/696,677, filed on Jul. 11, 2018.
Prior Publication US 2022/0127651 A1, Apr. 28, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. C12P 7/6409 (2022.01); C12N 1/20 (2006.01); C12R 1/225 (2006.01)
CPC C12P 7/6409 (2013.01) [C12N 1/205 (2021.05); C12P 2203/00 (2013.01); C12R 2001/225 (2021.05)] 20 Claims
 
1. A microbiome composition comprising a set of microbes, wherein the microbes in the set consist of members of Lachnospiraceae, Eubacteriaceae, Coriobacteriaceae, and Lactobacillusceae, wherein the number of individual physical microbes in the set constitutes at least 60% of the total number of individual physical microbes in the microbiome composition, wherein the members of Lachnospiraceae constitute at least 40% of the total number of individual physical microbes in the microbiome composition, the members of Eubacteriaceae constitute at least 2% of the total number of individual physical microbes in the microbiome composition, the members of Coriobacteriaceae constitute at least 3% of the total number of individual physical microbes in the microbiome composition, and the members of Lactobacilluseae constitute at least 7% of the total number of individual physical microbes in the microbiome composition.