US 12,304,917 B1
Pleuromutilin derivative containing a thiazolo[5,4-c]pyridine side chain, and a preparation method and application thereof
Chengyuan Liang, Shaanxi (CN); Yanzi Wang, Shaanxi (CN); Bingxing Zhang, Shaanxi (CN); Wen Wang, Shaanxi (CN); and Yunfei Zhang, Shaanxi (CN)
Assigned to SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY, Xi'an (CN)
Filed by SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY, Shaanxi (CN)
Filed on Nov. 18, 2024, as Appl. No. 18/951,543.
Claims priority of application No. 202410603855.7 (CN), filed on May 15, 2024.
Int. Cl. C07D 513/04 (2006.01); A61K 31/437 (2006.01); A61P 31/04 (2006.01); C07C 303/28 (2006.01)
CPC C07D 513/04 (2013.01) [A61K 31/437 (2013.01); A61P 31/04 (2018.01); C07C 303/28 (2013.01); C07C 2603/82 (2017.05)] 11 Claims
OG exemplary drawing
 
1. A compound of formula I, a pharmaceutically acceptable salt, or a tautomer thereof:

OG Complex Work Unit Chemistry
wherein R is a phenyl group substituted with an electron withdrawing group or a phenyl group substituted with an electron donating group.