US 12,304,901 B2
Selective ligands for tau aggregates
Daniel Dungan Sohn, Södertälje (SE)
Assigned to Sentonix, Inc., Arlington, MA (US)
Filed by Sentonix, Inc., Arlington, MA (US)
Filed on Oct. 28, 2024, as Appl. No. 18/929,263.
Application 18/929,263 is a continuation of application No. PCT/EP2023/080605, filed on Nov. 2, 2023.
Claims priority of application No. 2216351.3 (GB), filed on Nov. 3, 2022; and application No. 2312590.9 (GB), filed on Aug. 17, 2023.
Prior Publication US 2025/0066330 A1, Feb. 27, 2025
Int. Cl. C07D 401/14 (2006.01); A61K 31/4545 (2006.01); A61K 51/04 (2006.01); C07B 59/00 (2006.01)
CPC C07D 401/14 (2013.01) [A61K 31/4545 (2013.01); A61K 51/0455 (2013.01); C07B 59/002 (2013.01)] 18 Claims
 
1. A compound of formula (I)

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof,
wherein either:
R1 is OH, and R2 is H; or
R1 is H, and R2 is OH.