US 12,304,895 B2
2,3-diaryl-2,3-dihydro-4H-1,3-thiazin-4-one compounds and methods for making
Lee J. Silverberg, Allentown, PA (US); and John Tierney, West Chester, PA (US)
Assigned to THE PENN STATE RESEARCH FOUNDATION UNIVERSITY, University Park, PA (US)
Appl. No. 17/609,916
Filed by The Penn State Research Foundation, University Park, PA (US)
PCT Filed May 21, 2020, PCT No. PCT/US2020/034021
§ 371(c)(1), (2) Date Nov. 9, 2021,
PCT Pub. No. WO2020/237063, PCT Pub. Date Nov. 26, 2020.
Claims priority of provisional application 62/852,093, filed on May 23, 2019.
Prior Publication US 2022/0213046 A1, Jul. 7, 2022
Int. Cl. C07D 279/06 (2006.01); C07D 279/08 (2006.01); C07D 513/04 (2006.01)
CPC C07D 279/06 (2013.01) [C07D 279/08 (2013.01); C07D 513/04 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A compound of Formula I:

OG Complex Work Unit Chemistry
wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13 and R14 are each independently selected from the group consisting of H, halogen, nitro, cyano, amido, pyridyl, alkyl, aryl, acyl, alkoxy, cycloalkyl, heteroalkyl, heterocyclyl, aralkyl, heteroaryl and heteroaralkyl,
wherein R8 is not H or CH3, and
wherein R3 is not H, CH3 or an aza-aromatic group.