CPC C07D 265/26 (2013.01) [C07C 231/14 (2013.01); C07C 237/28 (2013.01); C07D 209/38 (2013.01)] | 17 Claims |
1. A method of preparing a compound of Formula VI, wherein
![]() each of R7-R10 is independently selected from hydrogen, halogen, halogenated C1-C5 alkyl, and C1-C5 alkyl;
wherein at least one of R7-R10 is a halogen; and
wherein R11 is selected from branched C1-C10 alkyl and unbranched C1-C10 alkyl, the method comprising
I) forming a mixture comprising
A) a compound of Formula V, wherein
![]() each of R7-R10 is independently selected from hydrogen, halogen, halogenated C1-C5 alkyl, and C1-C5 alkyl;
wherein at least one of R7-R10 is a halogen; and
wherein the compound of Formula V is prepared according to a method comprising
i) forming a first mixture comprising
a) a compound of Formula III, wherein
![]() each of R1-R4 is independently selected from hydrogen, halogen, and C1-C5 alkyl;
b) a solvent; and
c) a halogenation reagent;
ii) reacting the first mixture;
iii) adding an oxidation agent to the reacted first mixture in the presence of a catalyst to form a further mixture; and
iv) reacting the third mixture;
B) an alkylamine; and
C) a solvent; and
II) reacting the mixture.
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