US 12,303,463 B2
Female-female adapter
Scott Richard Ariagno, Inverness, IL (US); Mark Schilling, Mundelein, IL (US); Amey Mathakari, Mundelein, IL (US); Daniel Sanchez, Round Lake Beach, IL (US); and Christopher Blackledge, McHenry, IL (US)
Assigned to TAKEDA PHARMACEUTICAL COMPANY LIMITED, Osaka (JP)
Appl. No. 17/258,833
Filed by TAKEDA PHARMACEUTICAL COMPANY LIMITED, Osaka (JP)
PCT Filed Jul. 11, 2019, PCT No. PCT/US2019/041354
§ 371(c)(1), (2) Date Jan. 8, 2021,
PCT Pub. No. WO2020/014447, PCT Pub. Date Jan. 16, 2020.
Claims priority of provisional application 62/697,677, filed on Jul. 13, 2018.
Prior Publication US 2021/0290486 A1, Sep. 23, 2021
Int. Cl. A61J 1/20 (2006.01)
CPC A61J 1/2048 (2015.05) [A61J 1/2096 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A method of using a female-female adapter including a central lumen having a first end and a second end to reconstitute a lyophilized powder, the method comprising:
attaching a first end of a female-female adapter to a male nozzle of a syringe, the female-female adapter comprising wings extending parallel to the central lumen, each wing having a slat with a bow-tie shape, wherein each slat has an upper widest portion and a lower widest portion, and a narrowed middle portion between them;
pulling the female-female adapter axially, with the syringe and without touching the female-female adapter, such that the slats disengage from dual undercuts in a packaging, wherein each undercut engages the slat proximate the narrowed middle portion such that the lower widest portion of each slat is positioned below the respective undercut and the upper widest portion of each slat is positioned above the respective undercut;
removing the female-female adapter, with the female-female adapter attached to the syringe, from the packaging;
attaching a second end of the female-female adapter to a first component of a reconstitution device attached to a first vial, extracting a diluent from the first vial into the syringe;
disconnecting the syringe from the female-female adapter without touching the female-female adapter; and
reconstituting a lyophilized powder by attaching the male nozzle of the syringe to a second component of the reconstitution device attached to a second vial comprising the lyophilized powder and ejecting the diluent into the second vial.