US 12,303,313 B2
Method of and system for calcium scoring of coronary arteries
Casey Jack Clifton, Subiaco (AU); Jack Rex Joyner, Floreat (AU); Julien Charles Flack, Swanbourne (AU); Girish Dwivedi, Dalkeith (AU); and Abdul Rahman Ihdayhid, Ardross (AU)
Assigned to Artrya Limited, Perth (AU)
Appl. No. 17/802,890
Filed by Artrya Limited, Perth (AU)
PCT Filed Feb. 26, 2021, PCT No. PCT/AU2021/050168
§ 371(c)(1), (2) Date Aug. 26, 2022,
PCT Pub. No. WO2021/168517, PCT Pub. Date Sep. 2, 2021.
Claims priority of application No. 2020900593 (AU), filed on Feb. 28, 2020; application No. 2020902072 (AU), filed on Jun. 22, 2020; and application No. 2020902398 (AU), filed on Jul. 10, 2020.
Prior Publication US 2023/0117134 A1, Apr. 20, 2023
Int. Cl. A61B 6/00 (2024.01); A61B 6/50 (2024.01); G06T 7/10 (2017.01); G06T 7/62 (2017.01); G06T 11/00 (2006.01)
CPC A61B 6/504 (2013.01) [A61B 6/503 (2013.01); A61B 6/5217 (2013.01); G06T 7/10 (2017.01); G06T 7/62 (2017.01); G06T 11/003 (2013.01); G06T 2207/10081 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30101 (2013.01); G06T 2207/30204 (2013.01)] 27 Claims
OG exemplary drawing
 
1. A method of automatically determining a calcium score for at least one coronary component, the method comprising:
receiving cardiac non-contrast CT data indicative of a cardiac non-contrast CT scan carried out on a patient;
analysing the cardiac non-contrast CT data in a calcified components identifier to detect at least one candidate coronary calcified component associated with at least one target coronary anatomical structure;
analysing cardiac non-contrast CT data associated with the at least one candidate coronary calcified component using a radiomics analyser to determine radiomic characteristics of the at least one candidate coronary calcified component;
applying machine learning to the determined radiomic characteristics associated with each candidate coronary calcified component to identify any calcifications that are located on the at least one target coronary anatomical structure;
analysing the cardiac non-contrast CT data to identify at least one body component in the cardiac non-contrast CT data not associated with the at least one target coronary anatomical structure; and
after identifying any calcifications that are located on a coronary artery, using the identified at least one body component in the cardiac non-contrast CT data to remove misclassification of calcifications on the at least one coronary target anatomical structure that are located on the at least one identified body component.