US 11,982,655 B2
Analysis apparatus having a plurality of liquid chromatographs and its analysis method
Daisuke Akieda, Tokyo (JP); Makoto Nogami, Tokyo (JP); Iwao Suzuki, Tokyo (JP); Masako Kawarai, Tokyo (JP); Izumi Ogata, Tokyo (JP); and Shinya Ito, Tokyo (JP)
Assigned to Hitachi High-Tech Corporation, Tokyo (JP)
Appl. No. 17/295,345
Filed by Hitachi High-Tech Corporation, Tokyo (JP)
PCT Filed Nov. 19, 2019, PCT No. PCT/JP2019/045240
§ 371(c)(1), (2) Date May 19, 2021,
PCT Pub. No. WO2020/105624, PCT Pub. Date May 28, 2020.
Claims priority of application No. 2018-217157 (JP), filed on Nov. 20, 2018.
Prior Publication US 2021/0389287 A1, Dec. 16, 2021
Int. Cl. G01N 30/86 (2006.01); G01N 30/02 (2006.01); G01N 30/24 (2006.01); G01N 30/34 (2006.01); G01N 30/46 (2006.01); G01N 30/62 (2006.01); G01N 30/72 (2006.01)
CPC G01N 30/86 (2013.01) [G01N 30/46 (2013.01); G01N 30/466 (2013.01); G01N 30/7233 (2013.01); G01N 2030/027 (2013.01); G01N 30/24 (2013.01); G01N 30/34 (2013.01); G01N 2030/628 (2013.01)] 11 Claims
OG exemplary drawing
 
1. An analysis apparatus having a plurality of liquid chromatographs, comprising:
the multiple liquid chromatographs each of which comprises a separation column to receive a sample and separate the received same into components;
a detector to detect the components of the sample fed from each of the multiple liquid chromatographs;
a data processing unit to process detection data detected by the detector; a device control unit to control the multiple liquid chromatographs and the detector; and
an output unit,
wherein the device control unit judges a device status of the multiple liquid chromatographs in accordance with data that is obtained by detecting a measurement object sample and a non-retaining ingredient sample introduced into any one of the multiple liquid chromatographs by the detector and that is processed by the data processing unit;
wherein the device control unit judges a device status of the multiple liquid chromatographs on the basis of peak separation performance of the measurement object sample and fluctuation of retention time of the non-retaining ingredient sample;
wherein the device control unit judges whether or not peak separation performance of the measurement object sample is within a peak separation allowable range, outputs a separation column replacement instruction to the output unit when fluctuation of retention time of the non-retaining ingredient sample is within a fluctuation allowable range, and outputs a device maintenance instruction to the output unit when the peak separation performance is not within the peak separation allowable range and the fluctuation of the retention time of the non-retaining ingredient sample is not within the fluctuation allowable range.