US 11,982,611 B2
Systems, apparatuses, and methods for cell sorting and flow cytometry
Sunghwan Cho, San Diego, CA (US); Jose Manuel Morachis, San Diego, CA (US); Ivan Gagne, San Diego, CA (US); Rick Segil, San Diego, CA (US); William Arthur Alaynick, San Diego, CA (US); Zhe Mei, San Diego, CA (US); Sean Phillips, San Diego, CA (US); Chien-Chun Yang, San Diego, CA (US); Dongseob Yun, San Diego, CA (US); Michael Jerome Benchimol, San Diego, CA (US); Manna Doud, San Diego, CA (US); Nicholas Sullivan, San Diego, CA (US); and Constance Ardila, San Diego, CA (US)
Assigned to NANOCELLECT BIOMEDICAL, INC., San Diego, CA (US)
Appl. No. 16/495,738
Filed by NANOCELLECT BIOMEDICAL, INC., San Diego, CA (US)
PCT Filed Mar. 20, 2018, PCT No. PCT/US2018/023324
§ 371(c)(1), (2) Date Sep. 19, 2019,
PCT Pub. No. WO2018/175411, PCT Pub. Date Sep. 27, 2018.
Claims priority of provisional application 62/473,759, filed on Mar. 20, 2017.
Prior Publication US 2020/0200670 A1, Jun. 25, 2020
Int. Cl. B01L 3/00 (2006.01); B07C 5/342 (2006.01); G01N 15/14 (2006.01); G01N 15/10 (2006.01); G01N 15/149 (2024.01)
CPC G01N 15/1425 (2013.01) [B01L 3/502715 (2013.01); B01L 3/502746 (2013.01); B01L 3/502761 (2013.01); B07C 5/342 (2013.01); G01N 15/1484 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0819 (2013.01); B01L 2400/082 (2013.01); G01N 2015/1006 (2013.01); G01N 15/149 (2024.01)] 10 Claims
OG exemplary drawing
 
1. An apparatus, comprising:
a slot for receiving a microfluidic chip having a set of first channels;
a set of second channels, each channel of the set of second channels coupleable to a different channel of the set of first channels during use with the microfluidic chip;
a fluid damper comprising one or more gas chambers in fluid communication with a first channel in the set of second channels, wherein the fluid damper reduces variations in the fluid flow rate by compression and expansion of a gas in the one or more gas chambers in response to fluid flow in the first channel; and
an indent configured for engagement and alignment of the apparatus during use,
such that the apparatus, upon insertion into a device, engages a first biasing member of the device configured for alignment of the apparatus in a first direction and to bias movement of the apparatus into locking position with a notch of the device.