US 11,982,593 B2
Real-time, non-destructive Container Closure Integrity measurement
Christian Eichhorn, Pottstown, PA (US); Sindhuja Kuchibhatla, Kendall Park, NJ (US); Michael Sullivan, Birdsboro, PA (US); and Kevin Gribowicz, Malvern, PA (US)
Assigned to West Pharmaceutical Services, Inc., Exton, PA (US)
Appl. No. 17/425,778
Filed by West Pharmaceutical Services, Inc., Exton, PA (US)
PCT Filed Jan. 25, 2020, PCT No. PCT/US2020/014908
§ 371(c)(1), (2) Date Jul. 26, 2021,
PCT Pub. No. WO2020/154570, PCT Pub. Date Jul. 30, 2020.
Claims priority of provisional application 62/796,886, filed on Jan. 25, 2019.
Prior Publication US 2022/0187155 A1, Jun. 16, 2022
Int. Cl. G01M 3/32 (2006.01); B65D 55/02 (2006.01)
CPC G01M 3/3209 (2013.01) [B65D 55/028 (2013.01); B65D 2203/10 (2013.01)] 30 Claims
OG exemplary drawing
 
1. A method for determining closure integrity of a container system, the container system comprising a container, an elastomeric stopper comprising an embedded positioning component, and a retainer for retaining the elastomeric stopper, and a cap comprising at least a portion of a detection system for detecting a position of the embedded positioning component, wherein the elastomeric stopper is confined between a rim of the container and the retainer to seal the container, the method comprising:
determining, using the detection system, the position of the embedded positioning component; and
determining, based on the position of the embedded positioning component, the closure integrity of the container system.