	US 11,981,753 B2
	Peptide compound and application thereof, and composition containing peptide compound
Yvonne Angell, Shanghai (CN); Yu Wu, Shanghai (CN); Yan Wang, Shanghai (CN); Weimin Liu, Shanghai (CN); Kin Chiu Fong, Shanghai (CN); Jie Wen, Shanghai (CN); and Yonghan Hu, Shanghai (CN)
Assigned to ShangPharma Innovation Inc., Wilmington, DE (US)
Filed by ShangPharma Innovation Inc., Wilmington, DE (US)
Filed on Apr. 22, 2022, as Appl. No. 17/726,604.
Application 17/726,604 is a division of application No. 16/628,586, granted, now 11,427,615, previously published as PCT/CN2018/094618, filed on Jul. 5, 2018.
Claims priority of application No. 201710543383.0 (CN), filed on Jul. 5, 2017; and application No. 201810725881.1 (CN), filed on Jul. 4, 2018.
Prior Publication US 2022/0242908 A1, Aug. 4, 2022
Int. Cl. A61K 47/60 (2017.01); A61P 35/04 (2006.01); C07K 7/06 (2006.01); A61K 38/00 (2006.01)

CPC C07K 7/06 (2013.01) [A61K 47/60 (2017.08); A61P 35/04 (2018.01); A61K 38/00 (2013.01)]

1 Claim

1. A method for treating diseases related to kisspeptin receptors in a subject in need thereof, comprising administering an effective amount of the compound YA-156, a pharmaceutically acceptable salt thereof, a tautomer thereof, or a solvate thereof, wherein the compound YA-156 is shown below:

Palm-PEG8-Gly-Gly-(D-Tyr)-Hyp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH₂,

wherein Palm is palmitoyl,

wherein said disease related to kisspeptin receptors is one or more of hormone-related diseases, wherein hormone-related disease is endometriosis.