US 11,981,743 B2
Monoclonal antibody and a method thereof
Ramakrishnan Melarkode, Bangalore (IN); Pradip Nair, Bangalore (IN); Sundaraj David Rajkumar, Tamilnadu (IN); Kedarnath Nanjund Sastry, Bangalore (IN); Monalisa Chatterji, Bangalore (IN); Laxmi Adhikary, Bangalore (IN); Hema Balasubramanian, Bangalore (IN); Jose Enrique Montero Casimiro, Habana (CU); Josefa Lombardero Valladares, Ciudad de la Habana (CU); and Rolando Perez Rodriguez, Ciudad de la Habana (CU)
Assigned to Biocon Limited, Bangalore (IN); and CENTRO DE INMUNOLOGIA MOLECULAR, Havana (CU)
Filed by BIOCON LIMITED, Bangalore (IN); and CENTRO DE INMUNOLOGIA MOLECULAR, Havana (CU)
Filed on Apr. 29, 2020, as Appl. No. 16/862,417.
Application 16/862,417 is a continuation of application No. 15/975,681, filed on May 9, 2018, granted, now 10,669,346.
Application 15/975,681 is a continuation of application No. 15/609,625, filed on May 31, 2017, granted, now 10,000,573.
Application 15/609,625 is a continuation of application No. 14/969,461, filed on Dec. 15, 2015, granted, now 9,670,285.
Application 14/969,461 is a continuation of application No. 14/016,318, filed on Sep. 3, 2013, granted, now 9,217,037.
Application 14/016,318 is a continuation of application No. 12/921,544, granted, now 8,524,233, previously published as PCT/IN2008/000562, filed on Sep. 4, 2008.
Claims priority of application No. 00650/CHE/2008 (IN), filed on Mar. 14, 2008.
Prior Publication US 2021/0122829 A1, Apr. 29, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01)
CPC C07K 16/2896 (2013.01) [A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/2809 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01)] 11 Claims
 
1. A humanized IgG1 monoclonal antibody that specifically binds to human CD6, comprising a heavy chain variable (VH) sequence set forth in SEQ ID NO:1, and a light chain variable (VK) sequence set forth in SEQ ID NO:2.