US 11,981,700 B2
Pyrrolopyrimidine nucleosides and analogs thereof
John Henry Bougher, III, Durham, NC (US); Ramamurty V S Changalvala, Durham, NC (US); Aaron Leigh Downey, Durham, NC (US); John C. Drach, Ann Arbor, MI (US); Ernest Randall Lanier, Jr., Durham, NC (US); Andrew Louis McIver, Durham, NC (US); Bradley David Robertson, Durham, NC (US); Dean Wallace Selleseth, Durham, NC (US); Phiroze Behram Sethna, Durham, NC (US); Leroy Townsend, Ann Arbor, MI (US); and Roy W. Ware, Durham, NC (US)
Assigned to Chimerix, Inc., Durham, NC (US); and The Regents of the University of Michigan, Ann Arbor, MI (US)
Filed by Chimerix, Inc., Durham, NC (US); and The Regents of the University of Michigan, Ann Arbor, MI (US)
Filed on Jan. 27, 2021, as Appl. No. 17/159,451.
Application 17/159,451 is a continuation of application No. 16/533,194, filed on Aug. 6, 2019, granted, now 10,941,175.
Application 16/533,194 is a continuation of application No. 15/599,056, filed on May 18, 2017, granted, now 10,407,457, issued on Sep. 10, 2019.
Application 15/599,056 is a continuation of application No. 15/358,938, filed on Nov. 22, 2016, granted, now 9,701,706, issued on Jul. 11, 2017.
Application 15/358,938 is a continuation of application No. 15/231,528, filed on Aug. 8, 2016, granted, now 9,708,359, issued on Jul. 18, 2017.
Claims priority of provisional application 62/202,010, filed on Aug. 6, 2015.
Claims priority of application No. 1606645 (GB), filed on Apr. 15, 2016.
Prior Publication US 2022/0002335 A1, Jan. 6, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07D 239/70 (2006.01); C07H 19/14 (2006.01); C07H 19/16 (2006.01); A61K 31/7052 (2006.01); A61K 31/706 (2006.01); A61K 31/7064 (2006.01)
CPC C07H 19/14 (2013.01) [C07D 239/70 (2013.01); C07H 19/16 (2013.01); A61K 31/7052 (2013.01); A61K 31/706 (2013.01); A61K 31/7064 (2013.01)] 13 Claims
 
1. A compound, wherein the compound is
 
Com-
 
pound
 
No. Structure
 
 
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or a pharmaceutically aceeptable salt, solvate, enantiomer,
diastereomer, racemate, or mixture thereof.