US 11,980,735 B2
Dynamic agent injection for cardiovascular characterization
Erick Louis Oberstar, Verona, WI (US); and Michael Antonio Speidel, Madison, WI (US)
Assigned to Wisconsin Alumni Research Foundation, Madison, WI (US)
Filed by Wisconsin Alumni Research Foundation, Madison, WI (US)
Filed on Aug. 7, 2019, as Appl. No. 16/534,725.
Prior Publication US 2021/0322668 A1, Oct. 21, 2021
Int. Cl. A61M 5/00 (2006.01); A61B 5/026 (2006.01); A61B 5/0275 (2006.01); A61B 6/00 (2006.01); A61B 6/03 (2006.01); A61B 6/50 (2024.01); A61B 8/06 (2006.01); A61B 8/08 (2006.01); A61M 5/14 (2006.01); A61M 5/145 (2006.01)
CPC A61M 5/007 (2013.01) [A61B 6/481 (2013.01); A61B 6/507 (2013.01); A61M 5/1408 (2013.01); A61M 5/1452 (2013.01); A61B 5/0263 (2013.01); A61B 5/0275 (2013.01); A61B 6/032 (2013.01); A61B 8/06 (2013.01); A61B 8/481 (2013.01); A61M 2205/3334 (2013.01); A61M 2230/04 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method comprising:
continuously injecting a liquid including an agent and another liquid into a vascular system, including dynamically modulating a flow rate of the agent within the liquid prior to the liquid being injected into the vascular system, relative to the other liquid, over a range of flow rates and therein causing the vascular system to exhibit a dynamic response to the dynamic modulation; and
characterizing the vascular system based on a time-varying characteristic of the dynamic modulation of the agent relative to the other liquid as it is being continuously injected, and based on the dynamic response of the vascular system to the dynamic modulation.