US 11,980,653 B2
Method and kit for bowel preparation
Steven Gorelick, Danbury, CT (US); Michael Schiffman, Weston, CT (US); Melody Olmstead, New Milford, CT (US); and Adam Gorelick, Woodbridge, CT (US)
Assigned to MSM Innovations, Inc., Weston, CT (US)
Filed by MSM Innovations, Inc., Weston, CT (US)
Filed on Jun. 27, 2022, as Appl. No. 17/849,887.
Application 17/849,887 is a continuation of application No. 16/394,621, filed on Apr. 25, 2019, abandoned.
Application 16/394,621 is a continuation of application No. 15/793,279, filed on Oct. 25, 2017, abandoned.
Application 15/793,279 is a continuation of application No. 15/405,489, filed on Jan. 13, 2017, abandoned.
Application 15/405,489 is a continuation of application No. 14/963,575, filed on Dec. 9, 2015, granted, now 9,585,937, issued on Mar. 7, 2017.
Application 14/963,575 is a continuation of application No. 13/957,857, filed on Aug. 2, 2013, granted, now 9,433,660, issued on Sep. 6, 2016.
Application 13/957,857 is a continuation in part of application No. 13/708,430, filed on Dec. 7, 2012, granted, now 9,238,075, issued on Jan. 19, 2016.
Claims priority of provisional application 61/679,183, filed on Aug. 3, 2012.
Claims priority of provisional application 61/568,131, filed on Dec. 7, 2011.
Prior Publication US 2022/0339242 A1, Oct. 27, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 38/16 (2006.01); A61K 9/00 (2006.01); A61K 36/185 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01); A61K 47/34 (2017.01); A61K 47/36 (2006.01); A61K 47/42 (2017.01)
CPC A61K 38/168 (2013.01) [A61K 9/0053 (2013.01); A61K 9/0095 (2013.01); A61K 36/185 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/34 (2013.01); A61K 47/36 (2013.01); A61K 47/42 (2013.01)] 15 Claims
 
1. A taste-modifying kit for reducing a salty taste of a liquid composition administered to a subject, the kit comprising: (i) a premeasured amount of at least one pH-modifying agent wherein the amount is sufficient to adjust the pH of the liquid composition to a pH ranging from 1 to 6.9, (ii) miraculin, (iii) the liquid composition, and (iv) instruction material indicating that the salty taste of the liquid composition is to be reduced by a method comprising the steps of:
(a) determining the pH of the liquid composition, wherein the pH ranges from 1 to 6.9 or is adjusted to range from 1 to 6.9 using the at least one pH-modifying agent;
(b) providing miraculin to the subject; and
(c) administering orally the liquid composition to the subject after or when miraculin is provided,
wherein the liquid composition comprises greater than 3 grams/liter one or more alkali metal salts.