US 11,980,454 B2
Microcirculatory high-velocity blood flow threshold index and measurement and calculation system and method thereof
Xinghuai Feng, Xuzhou (CN); Hui Feng, Xuzhou (CN); Jie Shao, Xuzhou (CN); Jing Lu, Xuzhou (CN); and Yuanchang Zhang, Xuzhou (CN)
Assigned to XUZHOU LIHUA ELECTRONIC TECHNOLOGY DEVELOPMENT CO., LIMITED, Xuzhou (CN)
Filed by XUZHOU LIHUA ELECTRONIC TECHNOLOGY DEVELOPMENT CO., LIMITED, Xuzhou (CN)
Filed on Aug. 18, 2021, as Appl. No. 17/405,053.
Claims priority of application No. 202010905859.2 (CN), filed on Sep. 1, 2020.
Prior Publication US 2022/0061682 A1, Mar. 3, 2022
Int. Cl. A61B 5/026 (2006.01); A61B 5/00 (2006.01); G06T 7/00 (2017.01)
CPC A61B 5/0261 (2013.01) [A61B 5/0077 (2013.01); A61B 5/412 (2013.01); G06T 7/0012 (2013.01); G06T 2207/30104 (2013.01)] 8 Claims
OG exemplary drawing
 
1. A method for measurements and calculations of a microcirculatory high-velocity blood flow, comprising the following steps:
step 1: defining the microcirculatory high-velocity blood flow as a microcirculation manifestation of a macro-hemodynamic high output-low resistance phenomenon in a resting state, and setting a blood flow velocity of higher than 1,000 μm/s in an arteriole, a venule, and a true capillary exchange network of a microcirculatory capillary circuitous channel as an initial threshold for the microcirculatory high-velocity blood flow;
step 2: using a microcirculation observation device to select 3 to 5 observation regions at a sublingual mucosa or any other part of a body that allows microcirculation observation and recording videos of the 3 to 5 observation regions; comparing the videos of the 3 to 5 observation regions, selecting a video with a highest blood flow velocity from the videos with blood vessels with blood flow velocity higher than 1,000 μm/s as a high-velocity blood flow candidate sample, and saving the high-velocity blood flow candidate sample in a sample database; and then in the high-velocity blood flow candidate sample selecting a blood vessel with a highest blood flow velocity as a candidate blood vessel sample of the high-velocity blood flow candidate blood vessel sample, without considering a diameter of the blood vessel; and
step 3: tracking a trajectory of RBCs, WBCs, or plasma particles in the microcirculatory high-velocity blood flow on a display screen, calculating a traveling distance and a traveling time of the RBCs, the WBCs, or the plasma particles with an aid of a computer, and dividing the traveling distance by the traveling time to calculate an average blood flow velocity of the microcirculatory high-velocity blood flow.