US 11,980,218 B2
Dust-free cold-water-dispersible preparations
Kathrin Meyer-Boehm, Ludwigshafen am Rhein (DE); Andreas Habich, Ludwigshafen am Rhein (DE); Daniel Wagner, Lampertheim (DE); Wolf Pelletier, Lampertheim (DE); Walter Dobler, Ludwigshafen am Rhein (DE); Peter Schording, Bubenheim (DE); and Karl Kolter, Ludwigshafen am Rhein (DE)
Assigned to BASF SE, Ludwigshafen am Rhein (DE)
Appl. No. 17/256,385
Filed by BASF SE, Ludwigshafen am Rhein (DE)
PCT Filed May 29, 2019, PCT No. PCT/EP2019/063894
§ 371(c)(1), (2) Date Dec. 28, 2020,
PCT Pub. No. WO2020/001906, PCT Pub. Date Jan. 2, 2020.
Claims priority of application No. 18180115 (EP), filed on Jun. 27, 2018.
Prior Publication US 2021/0153540 A1, May 27, 2021
Int. Cl. A23P 10/47 (2016.01); A23L 33/10 (2016.01); A61K 8/02 (2006.01); A61K 8/25 (2006.01); A61K 9/16 (2006.01)
CPC A23P 10/47 (2016.08) [A23L 33/10 (2016.08); A61K 8/022 (2013.01); A61K 8/25 (2013.01); A61K 9/1611 (2013.01); A61K 9/1682 (2013.01); A61K 2800/10 (2013.01); A61K 2800/412 (2013.01); A61K 2800/612 (2013.01); A61K 2800/621 (2013.01); A61K 2800/63 (2013.01)] 13 Claims
 
1. A particle comprising at least one water-insoluble or only sparingly water-soluble active substance that is coated with one or more layers, wherein the outermost one or more layers comprises one or more hydrophobic powdering agents on which at least one dispersant is absorbed;
in which the at least one dispersant has an HLB value of 0.5 to 13;
in which the hydrophobic powdering agent is hydrophobized silica; and
wherein the at least one dispersant comprises medium chain triglyceride (MCT) oil and in which the ration of hydrophobized silica to MCT oil is 0.2 to 1.2 based on 100 g of particles.