US 12,299,564 B2
Pattern discovery, prediction and causal effect estimation in treatment discontinuation
Celia Cintas, Nairobi (KE); Victor Abayomi Akinwande, Karen (KE); Aisha Walcott, Nairobi (KE); Ramya Raghavendra, New York, NY (US); and Komminist Weldemariam, Ottawa (CA)
Assigned to International Business Machines Corporation, Armonk, NY (US)
Filed by International Business Machines Corporation, Armonk, NY (US)
Filed on Dec. 23, 2020, as Appl. No. 17/133,285.
Prior Publication US 2022/0198265 A1, Jun. 23, 2022
Int. Cl. G06N 3/08 (2023.01); G06F 18/21 (2023.01); G06F 18/2132 (2023.01); G06F 18/40 (2023.01); G06N 3/044 (2023.01); G16H 20/00 (2018.01); G16H 50/20 (2018.01); G16H 50/70 (2018.01)
CPC G06N 3/08 (2013.01) [G06F 18/2132 (2023.01); G06F 18/217 (2023.01); G06F 18/40 (2023.01); G06N 3/044 (2023.01); G16H 20/00 (2018.01); G16H 50/20 (2018.01); G16H 50/70 (2018.01)] 20 Claims
OG exemplary drawing
 
1. A method comprising:
with a trained, computerized discontinuation predictor machine learning component, predicting, based on an input time series, a time when a subject will discontinue a course of medical treatment;
with a trained, computerized pattern behavior extractor machine learning component, extracting from said input time series a top k discriminatory sequences via discriminatory sub-sequence mining by comparing two or more subgroups and performing mining in search of patterns that appear unequally in the two or more subgroups, wherein said top k discriminatory sequences differentiate between first and second classes of interest to provide a hypothesis for downstream analysis of a cause of discontinuing said course of medical treatment;
with a trained, causal effect estimator computerized machine learning component, determining a reason why said subject will discontinue said course of medical treatment, based on said top k discriminatory sequences and additional data;
with a computerized user interface, providing said time when said subject will discontinue said course of medical treatment and said reason why said subject will discontinue said course of medical treatment to a responsible party to initiate an intervention; and
initiating said intervention to maintain said course of medical treatment.