US 12,298,312 B2
Detection of Lyme disease
Jyotsna S. Shah, Santa Clara, CA (US); Song Liu, San Jose, CA (US); and Sudhir Shah, Santa Clara, CA (US)
Assigned to ID-Fish Technology, Inc., Milpitas, CA (US)
Filed by ID-Fish Technology, Inc., Milpitas, CA (US)
Filed on Apr. 13, 2021, as Appl. No. 17/229,773.
Claims priority of provisional application 63/009,216, filed on Apr. 13, 2020.
Prior Publication US 2021/0325393 A1, Oct. 21, 2021
Int. Cl. G01N 33/577 (2006.01); G01N 33/535 (2006.01)
CPC G01N 33/577 (2013.01) [G01N 33/535 (2013.01); G01N 2333/916 (2013.01); G01N 2469/20 (2013.01); G01N 2800/26 (2013.01)] 20 Claims
 
1. A panel for detecting IgM- or IgG-class antibodies, the panel comprising:
a C6 chimera consisting of SEQ ID NO: 45; and
a plurality of groups of labelled and/or tagged and/or bound amino acid sequences, wherein labelled and/or tagged amino acid sequence is labelled and/or tagged with a detectable moiety, and wherein the plurality of groups of labelled and/or tagged and/or bound amino acid sequences is selected from the following groups:
(i) SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, and SEQ ID NO: 10,
(ii) SEQ ID NO: 21, SEQ ID NO: 22, SEQ ID NO: 23, SEQ ID NO: 24, SEQ ID NO: 25, and SEQ ID NO: 26,
(iii) SEQ ID NO: 32 and SEQ ID NO: 33,
(iv) SEQ ID NO: 27 and SEQ ID NO: 28;
(v) SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 15, SEQ ID NO: 16, SEQ ID NO: 17, SEQ ID NO: 18, SEQ ID NO: 19, and SEQ ID NO: 20,
(vi) SEQ ID NO: 34, SEQ ID NO: 35, SEQ ID NO: 36, SEQ ID NO: 37, SEQ ID NO: 38, and SEQ ID NO: 39,
(vii) SEQ ID NO: 29,
(viii) SEQ ID NO: 30,
(ix) SEQ ID NO: 31,
(x) SEQ ID NO: 40,
(xi) SEQ ID NOs: 41 and 42, and
(xii) SEQ ID NO: 43.