US 12,297,417 B2
Lateral filter array microfluidic device
Zhonghui Hugh Fan, Gainesville, FL (US); and Kangfu Chen, Gainesville, FL (US)
Assigned to UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED, Orlando, FL (US)
Appl. No. 17/270,167
Filed by UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED, Gainesville, FL (US)
PCT Filed Aug. 21, 2019, PCT No. PCT/US2019/047505
§ 371(c)(1), (2) Date Feb. 22, 2021,
PCT Pub. No. WO2020/041471, PCT Pub. Date Feb. 27, 2020.
Claims priority of provisional application 62/720,592, filed on Aug. 21, 2018.
Prior Publication US 2021/0236992 A1, Aug. 5, 2021
Int. Cl. B01D 61/14 (2006.01); B01D 61/18 (2006.01); B01D 63/00 (2006.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 1/26 (2006.01); C12M 3/06 (2006.01); G01N 33/543 (2006.01); G01N 33/574 (2006.01)
CPC C12M 33/14 (2013.01) [B01D 61/147 (2013.01); B01D 61/18 (2013.01); B01D 63/005 (2013.01); C12M 23/14 (2013.01); C12M 23/16 (2013.01); C12M 25/10 (2013.01); C12M 47/04 (2013.01); G01N 33/54366 (2013.01); G01N 33/57492 (2013.01); B01D 2313/08 (2013.01); B01D 2313/40 (2013.01)] 26 Claims
OG exemplary drawing
 
1. A lateral filter array microfluidic device for capturing a target isolate in a liquid sample, the device comprising
a substrate; and
at least one series of boundaries associated with the substrate,
wherein the at least one series of boundaries are arranged to define at least one serpentine main channel coupled with an inlet and an outlet that allows flow of the liquid sample in serpentine flow pattern, and
wherein the at least one series of boundaries comprise a plurality of filters with apertures that connect two sections of the serpentine main channel thereby allowing lateral flow of the liquid sample between the two sections.