US 12,296,044 B2
Gel for treating periocular and/or orbital pathologies and conditions
Morgan V. Fedorchak, Mars, PA (US); Jenny Yu, Pittsburgh, PA (US); and Michael A. Washington, Pittsburgh, PA (US)
Assigned to University of Pittsburgh-Of the Commonwealth System of Higher Education, Pittsburgh, PA (US)
Filed by University of Pittsburgh-Of the Commonwealth System of Higher Education, Pittsburgh, PA (US)
Filed on Jun. 2, 2022, as Appl. No. 17/830,995.
Application 17/830,995 is a division of application No. 16/764,285, granted, now 11,382,862, previously published as PCT/US2018/061227, filed on Nov. 15, 2018.
Claims priority of provisional application 62/587,270, filed on Nov. 16, 2017.
Prior Publication US 2022/0296512 A1, Sep. 22, 2022
Int. Cl. A61K 9/06 (2006.01); A61K 9/00 (2006.01); A61K 31/573 (2006.01); A61K 47/32 (2006.01); A61K 47/36 (2006.01); A61L 27/16 (2006.01); A61L 27/26 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01)
CPC A61K 9/06 (2013.01) [A61K 9/0048 (2013.01); A61K 31/573 (2013.01); A61K 47/32 (2013.01); A61K 47/36 (2013.01); A61L 27/16 (2013.01); A61L 27/26 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 2300/222 (2013.01); A61L 2430/16 (2013.01)] 29 Claims
OG exemplary drawing
 
1. A method comprising treating a periocular wound in a subject, comprising topically administering to the periocular wound a composition comprising a thermoresponsive gel, wherein the thermoresponsive gel comprises a copolymer of (a) N-isopropylacrylamide and (b) at least one acrylic monomer or at least one methacrylic monomer.