US 12,296,024 B2
Modified zinc oxide nanocomposite, antibiotic composition comprising the same, and combination preparation with the same
Yong Shin, Seoul (KR); and Huifang Liu, Seoul (KR)
Assigned to UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY, Seoul (KR)
Filed by UIF (University Industry Foundation), Yonsei University, Seoul (KR)
Filed on Jul. 7, 2022, as Appl. No. 17/859,724.
Claims priority of application No. 10-2021-0090179 (KR), filed on Jul. 9, 2021.
Prior Publication US 2023/0027034 A1, Jan. 26, 2023
Int. Cl. A61K 31/496 (2006.01); A61K 31/7048 (2006.01); A61K 33/30 (2006.01); A61K 47/69 (2017.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01); C01G 9/02 (2006.01)
CPC A61K 47/6929 (2017.08) [A61K 31/496 (2013.01); A61K 31/7048 (2013.01); A61K 33/30 (2013.01); A61K 47/6923 (2017.08); A61P 31/04 (2018.01); A61P 31/10 (2018.01); C01G 9/02 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A modified zinc oxide nanocomposite comprising zinc oxide nanocrystals modified with a compound represented by the following Chemical Formula 1:

OG Complex Work Unit Chemistry
wherein, in Chemical Formula 1, X is (CH2)n, and n is an integer from 5 to 10,
wherein the modified zinc oxide nanocomposite is prepared by mixing a salt of the compound represented by Chemical Formula 1 with the zinc oxide nanocrystals in a manner sufficient to provide for modified zinc oxide nanocrystals,
wherein the zinc oxide nanocrystals are crystals having a spindle shape.