	US 12,295,981 B2
	*Pharmaceutical composition for preventing or treating neurodegenerative diseases, containing Angelica gigas* Nakai extract or mixed extract of Angelica gigas Nakai and broccoli**
Kang Hyun Lee, Seoul (KR); and Min Kuk, Seoul (KR)
Assigned to ASTROGENESIS CO., LTD., Seoul (KR)
Appl. No. 17/280,975
Filed by Astrogenesis Co., Ltd., Seoul (KR)
PCT Filed Jul. 2, 2019, PCT No. PCT/KR2019/008062 § 371(c)(1), (2) Date Mar. 29, 2021, PCT Pub. No. WO2020/071620, PCT Pub. Date Apr. 9, 2020.
Claims priority of application No. 10-2018-0116945 (KR), filed on Oct. 1, 2018.
Prior Publication US 2021/0353698 A1, Nov. 18, 2021
Int. Cl. A61K 36/232 (2006.01); A23L 33/105 (2016.01); A61K 36/31 (2006.01); A61P 25/28 (2006.01)

CPC A61K 36/232 (2013.01) [A23L 33/105 (2016.08); A61K 36/31 (2013.01); A61P 25/28 (2018.01); A23V 2002/00 (2013.01)]

5 Claims

1. A method for treating neurodegenerative diseases, comprising administrating a mixed extract of Angelica gigas Nakai and Brassica oleracea var. italica to a subject in need thereof,

wherein the mixed extract of Angelica gigas Nakai and Brassica oleracea var. italic comprises:

an extract obtained by extracting Angelica gigas Nakai with 90 to 100% (v/v) ethanol at 40 to 60° C., and a Brassica oleracea var. italic ethanol extract obtained by extracting Brassica oleracea var. italica with 20 to 80% (v/v) ethanol at 10 to 80° C.,

wherein a mixing ratio between Angelica gigas Nakai extract and Brassica oleracea var. italica extract in the mixed extract is 1:1.5 to 10 based on the weight (the weight of Angelica gigas Nakai extract: the weight of Brassica oleracea var. italica extract).