	US 12,295,923 B2
	Antimicrobial compositions with 1,2-alkanediols
Rajan B. Bodkhe, Woodbury, MN (US); Ranjani V. Parthasarathy, Woodbury, MN (US); Matthew T. Scholz, Woodbury, MN (US); Naimul Karim, Maplewood, MN (US); Petra L. Kohler Riedi, Minneapolis, MN (US); and Joseph J. Stoffel, Hastings, MN (US)
Assigned to Solventum Intellectual Properties Company, Maplewood, MN (US)
Appl. No. 17/418,718
Filed by Solventum Intellectual Properties Company, Maplewood, MN (US)
PCT Filed Dec. 23, 2019, PCT No. PCT/IB2019/061284 § 371(c)(1), (2) Date Jun. 25, 2021, PCT Pub. No. WO2020/136552, PCT Pub. Date Jul. 2, 2020.
Claims priority of provisional application 62/785,365, filed on Dec. 27, 2018.
Prior Publication US 2022/0079893 A1, Mar. 17, 2022
Int. Cl. A61K 31/14 (2006.01); A01N 31/02 (2006.01); A01N 37/06 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01); A61K 47/14 (2017.01); A61K 47/18 (2017.01); A61K 47/32 (2006.01); A61P 31/02 (2006.01); A01N 33/04 (2006.01); A01N 37/04 (2006.01)

CPC A61K 31/14 (2013.01) [A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/14 (2013.01); A61K 47/183 (2013.01); A61K 47/32 (2013.01); A61P 31/02 (2018.01)]

15 Claims

1. An antiseptic composition, comprising:

a quaternary ammonium antiseptic component present in an amount of at least 0.04% by weight, the quaternary ammonium antiseptic component being a benzalkonium halide;

a polycarboxylic acid chelator of one or more of citric acid and citrate present in a concentration of at least 0.05 M;

a (C8-C12) 1,2 alkane diol; and

water;

wherein the antiseptic composition is characterized by a pH that is greater than or equal to 3.5 and less than 5.5 at 23° C.;

wherein the water is present in the antiseptic composition at a greater weight percent than each of the quaternary ammonium antiseptic component, the polycarboxylic acid chelator, and the (C8-C12) 1,2-alkane diol.