| CPC A61B 8/42 (2013.01) [A61B 34/20 (2016.02); A61B 8/4416 (2013.01)] | 24 Claims |

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1. A mixed reality (MR) visualization system, comprising:
an MR device comprising a holographic display configured to display a holographic image to an operator;
a hand-held ultrasound imaging device configured to obtain a real-time ultrasound image of a subject's anatomy; and
a computing device communicatively coupled to the MR device and the hand-held ultrasound imaging device, the computing device comprising a non-volatile memory and a processor, wherein the computing device is configured to:
receive the real-time ultrasound image;
determine a real-time 3D position and orientation of the hand-held ultrasound imaging device;
generate a modified real-time ultrasound image by modifying the real-time ultrasound image to correspond to the real-time 3D position and orientation of the hand-held ultrasound imaging device; and
transmit the modified real-time ultrasound image to the MR device for display as the holographic image positioned at a predetermined location relative to the hand-held ultrasound imaging device.
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