| CPC A61B 5/6866 (2013.01) [A61B 5/14503 (2013.01); A61B 5/14532 (2013.01); A61B 5/4839 (2013.01); A61M 1/282 (2014.02); A61M 1/287 (2013.01)] | 19 Claims |

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1. A method comprising:
controlling, by control circuitry, a peritoneal dialysis (PD) device to deliver PD therapy to a patient during a current PD cycle;
determining, by the control circuitry, a blood glucose level of the patient during the current PD cycle;
determining, by the control circuitry, the blood glucose level is greater than or equal to a predetermined blood glucose level threshold during the current PD cycle;
controlling, by the control circuitry and in response to determining the blood glucose level is greater than or equal to the predetermined blood glucose level threshold, a medical device to deliver insulin to the patient during the current PD cycle; and
in response to the medical device delivering insulin to the patient during the current PD cycle, determining, by the control circuitry a modification to a parameter of the PD therapy during the current PD cycle, wherein the parameter comprises at least one of a dialysate glucose concentration, an alternate osmotic solute concentration, a PD dialysate volume, a PD dialysate dwell time, an ultrafiltration volume, or a number of PD cycles within a time period.
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