US 12,295,751 B2
Eliminating acquisition-related artifacts in electrophysiological recording
Ryan Orin Melman, Sydney (AU); Justin James Gilmour, Sydney (AU); Alex von Brasch, Sydney (AU); and Todd Lupton, Sydney (AU)
Assigned to Cochlear Limited, Macquarie University (AU)
Filed by Cochlear Limited, Macquarie University (AU)
Filed on Nov. 26, 2019, as Appl. No. 16/696,021.
Application 16/696,021 is a continuation of application No. 15/361,356, filed on Nov. 25, 2016, granted, now 10,499,854.
Prior Publication US 2020/0093437 A1, Mar. 26, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/24 (2021.01); A61B 5/00 (2006.01); A61B 5/316 (2021.01); A61N 1/05 (2006.01); A61B 5/12 (2006.01); A61N 1/36 (2006.01)
CPC A61B 5/686 (2013.01) [A61B 5/24 (2021.01); A61B 5/316 (2021.01); A61B 5/7217 (2013.01); A61N 1/0541 (2013.01); A61B 5/12 (2013.01); A61N 1/36 (2013.01); A61N 1/36036 (2017.08)] 20 Claims
OG exemplary drawing
 
1. A method, comprising:
applying at least a first electrical stimulus to at least one stimulating electrode of an implantable medical device, the at least one stimulating electrode being set to a first polarity;
acquiring, via a set of recording electrodes, a first trace corresponding to one or more in vivo signals evoked in response to the at least first electrical stimulus during one or more first recording probe epochs during which the set of recording electrodes are set to the first polarity, wherein, when the set of recording electrodes are set to the first polarity, a first recording electrode of the set of recording electrodes is connected to a positive input and a second recording electrode of the set of recording electrodes is connected to a negative input;
switching connections associated with the set of recording electrodes such that the first recording electrode is connected to the negative input and the second recording electrode is connected to the positive input to change a polarity of the set of recording electrodes from the first polarity to a second polarity, wherein the second polarity is inverted relative to the first polarity;
applying at least a second electrical stimulus to the at least one stimulating electrode of the implantable medical device while the at least one stimulating electrode is set to the first polarity;
acquiring, via the set of recording electrodes, a second trace corresponding to one or more in vivo signals evoked in response to the at least second electrical stimulus during one or more second recording epochs during which the at least one stimulating electrode is set to the first polarity and the set of recording electrodes are set to the second polarity; and
obtaining a signal with a reduced acquisition artifact based on the first trace and the second trace.