US 12,295,737 B2
Diagnostic system and methods for simultaneously detecting light at multiple detection locations in a spectroscopic system
David Bannon, Hopkinton, MA (US); Domhnull Granquist-Fraser, Acton, MA (US); Paul Bartel, Woburn, MA (US); Kevin Didona, Chelmsford, MA (US); Carson Roberts, Roslindale, MA (US); and Blair Simon, Clinton, MA (US)
Assigned to Headwall Photonics, Inc., Bolton, MA (US)
Filed by Headwall Photonics, Inc., Bolton, MA (US)
Filed on Feb. 28, 2023, as Appl. No. 18/175,651.
Application 18/175,651 is a division of application No. 16/038,551, filed on Jul. 18, 2018, granted, now 11,642,070.
Claims priority of provisional application 62/645,621, filed on Mar. 20, 2018.
Claims priority of provisional application 62/533,865, filed on Jul. 18, 2017.
Prior Publication US 2023/0200717 A1, Jun. 29, 2023
Int. Cl. A61B 5/00 (2006.01)
CPC A61B 5/4064 (2013.01) [A61B 5/0075 (2013.01); A61B 5/4088 (2013.01); A61B 5/6814 (2013.01); A61B 5/0062 (2013.01); A61B 2562/0233 (2013.01); A61B 2562/0242 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A method for simultaneously detecting scattered light, deflected light, or a combination thereof from a target in a subject at a plurality of detection locations, the method comprising:
placing a sensor head on the subject proximal to the target, the sensor head comprising:
a housing;
an illumination output disposed on the housing, the illumination output coupled to an illumination source to supply light energy having an illumination wavelength range;
a plurality of light collection units disposed on the housing, each light collection unit comprising one or more polished ends of one or more respective optical fibers, each light collection unit disposed at a respective predetermined radial distance from the illumination output; and
wherein a number of polished ends in each light collection unit corresponds to the respective predetermined radial distance;
generating, with the illumination source, the light energy;
collecting, with at least one of the light collection units, at least one of scattered light and/or refracted light to provide collected light;
passing at least a portion of the collected light through a spectrometer to determine a spectral profile of the at least a portion of the collected light;
detecting the collected light with an optical sensor, the optical sensor electrically coupled to a computer; and
determining, with the computer, if current spectral scan data of the subject has a characteristic spectral signature indicative of neurological damage to or a neurological disease of a brain.
 
7. A method for simultaneously detecting scattered light, deflected light, or a combination thereof from a target in a subject at a plurality of detection locations, the method comprising:
placing a sensor head on the subject proximal to the target, the sensor head comprising:
a housing;
an illumination output disposed on the housing, the illumination output coupled to an illumination source to supply light energy having an illumination wavelength range;
a plurality of light collection units disposed on the housing, each light collection unit comprising one or more polished ends of one or more respective optical fibers, each light collection unit disposed at a respective predetermined radial distance from the illumination output; and
wherein a number of polished ends in each light collection unit corresponds to the respective predetermined radial distance;
generating, with the illumination source, the light energy;
collecting, with at least one of the light collection units, at least one of scattered light and/or refracted light to provide collected light;
passing at least a portion of the collected light through a spectrometer to determine a spectral profile of the at least a portion of the collected light;
detecting the collected light with an optical sensor, the optical sensor electrically coupled to a computer;
comparing, with the computer, current spectral scan data of the subject at the target with prior spectral scan data of the target to determine if a change in a spectral property of the target has occurred; and
wherein the change in the spectral property corresponds to neurological damage to or a neurological disease of a brain.