US 12,293,908 B2
Mass spectrometer with charge measurement arrangement
Martin F. Jarrold, Bloomington, IN (US); and David E. Clemmer, Bloomington, IN (US)
Assigned to THE TRUSTEES OF INDIANA UNIVERSITY, Bloomington, IN (US)
Appl. No. 17/781,483
Filed by THE TRUSTEES OF INDIANA UNIVERSITY, Bloomington, IN (US)
PCT Filed Dec. 16, 2020, PCT No. PCT/US2020/065301
§ 371(c)(1), (2) Date Jun. 1, 2022,
PCT Pub. No. WO2021/126972, PCT Pub. Date Jun. 24, 2021.
Claims priority of provisional application 62/949,554, filed on Dec. 18, 2019.
Prior Publication US 2023/0013173 A1, Jan. 19, 2023
Int. Cl. H01J 49/02 (2006.01); H01J 49/16 (2006.01); H01J 49/40 (2006.01); H01J 49/42 (2006.01)
CPC H01J 49/025 (2013.01) [H01J 49/027 (2013.01); H01J 49/165 (2013.01); H01J 49/40 (2013.01); H01J 49/421 (2013.01); H01J 49/422 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A mass spectrometer, comprising:
an ion source region including an ion generator configured to generate ions from a sample,
an ion detector configured to detect ions and produce corresponding ion detection signals,
an electric field-free drift region disposed between the ion source region and the ion detector through which the generated ions drift axially toward the ion detector,
a plurality of spaced-apart charge detection cylinders disposed in the drift region and through which the ions drifting axially through the drift region pass, and
a plurality of charge amplifiers each coupled to a different one of the plurality of charge detection cylinders and each configured to produce a charge detection signal corresponding to a magnitude of charge of one or more of the generated ions passing through a respective one of the plurality of charge detection cylinders.