| CPC G21K 5/08 (2013.01) [A61L 2/082 (2013.01); A61L 2/26 (2013.01); A61L 2202/11 (2013.01)] | 30 Claims | 

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               1. An irradiation system comprising: 
            a shielded housing; 
                at least one canister disposed within the shielded housing, the at least one canister containing a material for irradiation within an interior volume of the at least one canister; 
                wherein the at least one canister has a body disposed between a first end cap disposed at a first end of the canister and a second end cap disposed at a second end of the canister opposed to the first end; 
                an ionizing radiation source disposed within the shielded housing adapted for emitting an ionizing radiation having at least one selected incident irradiation field geometry directed generally at the body of the at least one canister; 
                wherein the at least one canister is disposed on a rotating mechanism for rotating the at least one canister about a central horizontal or longitudinal axis extending from an isocenter of the first end cap to an isocenter of the second end cap for increasing uniform distribution of radiation of the material contained within the canister; 
                wherein at least one of the first end cap and the second end cap includes a component configured for selectively constraining geometrically within an interior volume of the canister at least one of the material for irradiation and a containment device containing the material for irradiation for optimizing alignment to the at least one selected incident irradiation field geometry. 
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