US 12,292,441 B2
Recombinant Acinetobacter baumannii strain AB5075
Daniel V Zurawski, New Market, MD (US)
Assigned to The Government of the United States, as Represented by the Secretary of the Army, Fort Detrick, MD (US)
Filed by The Government of The United States, as represented by The Secretary of The Army, Fort Detrick, MD (US)
Filed on Mar. 3, 2021, as Appl. No. 17/191,490.
Application 17/191,490 is a division of application No. 15/505,375, granted, now 10,961,298, previously published as PCT/US2015/046221, filed on Aug. 21, 2015.
Claims priority of provisional application 62/040,407, filed on Aug. 21, 2014.
Prior Publication US 2021/0206840 A1, Jul. 8, 2021
Int. Cl. G01N 33/569 (2006.01); A61K 39/00 (2006.01); C07K 16/12 (2006.01); C12N 1/20 (2006.01)
CPC G01N 33/56911 (2013.01) [C07K 16/1203 (2013.01); C07K 16/1218 (2023.08); C12N 1/20 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); C07K 2317/70 (2013.01); G01N 2333/212 (2013.01)] 4 Claims
 
1. An Acinetobacter baumannii strain comprising a transposon comprising an antibiotic resistance gene and two loxP sites,
wherein the two loxP sites flank the antibiotic resistance gene,
wherein the transposon is inserted into the genome of the Acinetobacter baumannii and
interrupts the expression of hcp (hemolysin co-regulated protein),
wherein the strain is AB5075 deposited as Patent Deposit Number PTA-127747.