US 12,292,436 B2
Method for preserving urinary cells
Philipp Enghard, Berlin (DE); Paul Freund, Berlin (DE); Diana Metzke, Berlin (DE); and Christopher Skopnik, Berlin (DE)
Assigned to CHARITÉ-UNIVERSITÄTSMEDIZIN BERLIN, Berlin (DE)
Appl. No. 17/298,618
Filed by CHARITÉ-UNIVERSITÄTSMEDIZIN BERLIN, Berlin (DE)
PCT Filed Dec. 19, 2019, PCT No. PCT/EP2019/086433
§ 371(c)(1), (2) Date May 31, 2021,
PCT Pub. No. WO2020/127815, PCT Pub. Date Jun. 25, 2020.
Claims priority of application No. 18214037 (EP), filed on Dec. 19, 2018.
Prior Publication US 2022/0003748 A1, Jan. 6, 2022
Int. Cl. G01N 33/50 (2006.01); G01N 1/28 (2006.01); G01N 15/1404 (2024.01)
CPC G01N 33/5005 (2013.01) [G01N 1/28 (2013.01); G01N 15/1404 (2013.01); G01N 2800/34 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A method for analysing urinary cells, the method comprising the steps of:
contacting a urine sample obtained from a patient with
a. a buffer substance suitable to create and/or maintain a pH value in the range of 6 to 8, within said urine sample, and
b. a formaldehyde releasing compound
yielding a preserved urine sample,
storing the preserved sample prior to analysing the urinary cells at a temperature of −80° C. to 10° C.;
analysing urinary cells within said preserved urine sample.