US 12,292,364 B2
Enricher, enrichment system, sample manufacturing system, and sample detection system
Jianwen Ding, Changsha (CN)
Assigned to AVE SCIENCE & TECHNOLOGY CO., LTD., Changsha (CN)
Appl. No. 17/779,708
Filed by AVE SCIENCE & TECHNOLOGY CO., LTD., Changsha (CN)
PCT Filed Dec. 17, 2019, PCT No. PCT/CN2019/125838
§ 371(c)(1), (2) Date May 25, 2022,
PCT Pub. No. WO2021/103200, PCT Pub. Date Jun. 3, 2021.
Claims priority of application No. 201911181291.8 (CN), filed on Nov. 27, 2019.
Prior Publication US 2023/0038927 A1, Feb. 9, 2023
Int. Cl. G01N 21/25 (2006.01); G01N 1/30 (2006.01); G01N 1/40 (2006.01)
CPC G01N 1/4005 (2013.01) [G01N 1/30 (2013.01); G01N 1/40 (2013.01); G01N 21/25 (2013.01); G01N 2001/4088 (2013.01)] 18 Claims
OG exemplary drawing
 
1. An enricher, comprising:
an enriching housing enclosing an enriching cavity configured to receive a suction liquid, wherein the enriching housing is provided with a suction connection portion configured to be in communication with a suction mechanism and the enriching cavity, such that a negative pressure is generated in the enriching cavity under an action of the suction mechanism, wherein the enriching housing includes a bottom wall and a sidewall extending from an edge of the bottom wall in an axial direction, the enriching housing is further provided with a cushion body member configured to prevent the blocking member from recessing or breaking, and wherein a middle portion of the cushion body member protrudes beyond an outer surface of the bottom wall away from the enriching cavity; and
a blocking member provided on the cushion body member, wherein when negative pressure is generated in the enriching cavity, a sample is capable of penetrating the blocking member to form the suction liquid entering the enriching cavity, and a retentate is retained on the blocking member.