US 12,291,715 B2
Genetic locus imparting a low anatabine trait in tobacco and methods of using
Chengalrayan Kudithipudi, Midlothian, VA (US); Alec J. Hayes, Chesterfield, VA (US); Robert Frank Hart, III, Midlothian, VA (US); Yanxin Shen, Glen Allen, VA (US); Jesse Frederick, Richmond, VA (US); and Dongmei Xu, Glen Allen, VA (US)
Assigned to Altria Client Services LLC, Richmond, VA (US)
Filed by ALTRIA CLIENT SERVICES INC., Richmond, VA (US)
Filed on Dec. 4, 2023, as Appl. No. 18/527,834.
Application 18/527,834 is a continuation of application No. 17/683,227, filed on Feb. 28, 2022, granted, now 11,873,500.
Application 17/683,227 is a continuation of application No. 16/825,394, filed on Mar. 20, 2020, granted, now 11,299,743, issued on Apr. 12, 2022.
Application 16/825,394 is a continuation of application No. 14/794,092, filed on Jul. 8, 2015, granted, now 10,626,409, issued on Apr. 21, 2020.
Claims priority of provisional application 62/021,738, filed on Jul. 8, 2014.
Prior Publication US 2024/0117371 A1, Apr. 11, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. C12N 15/82 (2006.01); A01H 1/04 (2006.01); A01H 1/06 (2006.01); A01H 5/12 (2018.01); A01H 6/82 (2018.01); A24B 13/00 (2006.01); C12Q 1/6895 (2018.01)
CPC C12N 15/8261 (2013.01) [A01H 1/045 (2021.01); A01H 1/06 (2013.01); A01H 5/12 (2013.01); A01H 6/823 (2018.05); A24B 13/00 (2013.01); C12N 15/8218 (2013.01); C12N 15/8243 (2013.01); C12Q 1/6895 (2013.01); C12Q 2600/13 (2013.01); C12Q 2600/156 (2013.01)] 18 Claims
 
1. A tobacco plant having an induced mutation in an endogenous gene, wherein the endogenous gene encodes an amino acid sequence 100% identical to SEQ ID NO: 8, and wherein the tobacco plant having an induced mutation exhibits reduced expression or activity of a quinolinate synthase protein as compared to a control tobacco plant lacking the induced mutation.