US 12,291,709 B2
Compositions and methods for modulating apolipoprotein (a) expression
Thazha P. Prakash, Carlsbad, CA (US); Punit P. Seth, Carlsbad, CA (US); Eric E. Swayze, Encinitas, CA (US); and Mark J. Graham, San Clemente, CA (US)
Assigned to Ionis Pharmaceuticals, Inc., Carlsbad, CA (US)
Filed by Ionis Pharmaceuticals, Inc., Carlsbad, CA (US)
Filed on Nov. 3, 2023, as Appl. No. 18/501,779.
Application 18/501,779 is a continuation of application No. 17/060,440, filed on Oct. 1, 2020, granted, now 11,851,655.
Application 17/060,440 is a continuation of application No. 15/891,156, filed on Feb. 7, 2018, granted, now 10,883,104.
Application 15/891,156 is a continuation of application No. 14/839,580, filed on Aug. 28, 2015, granted, now 9,957,504.
Application 14/839,580 is a continuation of application No. 14/588,061, filed on Dec. 31, 2014, granted, now 9,181,550.
Application 14/588,061 is a continuation of application No. PCT/US2014/036460, filed on May 1, 2014.
Claims priority of provisional application 61/986,867, filed on Apr. 30, 2014.
Claims priority of provisional application 61/976,991, filed on Apr. 8, 2014.
Claims priority of provisional application 61/880,790, filed on Sep. 20, 2013.
Claims priority of provisional application 61/871,673, filed on Aug. 29, 2013.
Claims priority of provisional application 61/843,887, filed on Jul. 8, 2013.
Claims priority of provisional application 61/823,826, filed on May 15, 2013.
Claims priority of provisional application 61/818,442, filed on May 1, 2013.
Prior Publication US 2024/0352455 A1, Oct. 24, 2024
Int. Cl. C07H 21/04 A61K 31/7088 A61K 31/713 A61K 47/54 C12N 15/11 C12N 15/113
