US 12,291,652 B2
Zwitterionic double network hydrogels
Shaoyi Jiang, Seattle, WA (US); Hsiang-Chieh Hung, Seattle, WA (US); Dianyu Dong, Seattle, WA (US); Caroline Tsao, Seattle, WA (US); Chenjue Tang, Seattle, WA (US); and Joel MacArthur, Seattle, WA (US)
Assigned to University of Washington, Seattle, WA (US)
Appl. No. 17/268,310
Filed by University of Washington, Seattle, WA (US)
PCT Filed Aug. 14, 2019, PCT No. PCT/US2019/046558
§ 371(c)(1), (2) Date Feb. 12, 2021,
PCT Pub. No. WO2020/106338, PCT Pub. Date May 28, 2020.
Claims priority of provisional application 62/818,574, filed on Mar. 14, 2019.
Claims priority of provisional application 62/718,759, filed on Aug. 14, 2018.
Prior Publication US 2021/0171783 A1, Jun. 10, 2021
Int. Cl. C09D 5/16 (2006.01); A61L 24/00 (2006.01); A61L 27/34 (2006.01); A61L 27/52 (2006.01); A61L 29/08 (2006.01); A61L 29/14 (2006.01); A61L 31/10 (2006.01); A61L 31/14 (2006.01); C08F 267/10 (2006.01); C08J 3/075 (2006.01); C08J 3/24 (2006.01); C08L 51/00 (2006.01); C09D 151/00 (2006.01)
CPC C09D 5/1662 (2013.01) [A61L 24/0031 (2013.01); A61L 27/34 (2013.01); A61L 27/52 (2013.01); A61L 29/085 (2013.01); A61L 29/145 (2013.01); A61L 31/10 (2013.01); A61L 31/145 (2013.01); C08F 267/10 (2013.01); C08J 3/075 (2013.01); C08J 3/246 (2013.01); C08L 51/003 (2013.01); C09D 5/1637 (2013.01); C09D 151/003 (2013.01); C08J 2300/208 (2013.01); C08J 2333/14 (2013.01); C08J 2333/22 (2013.01); C08J 2333/24 (2013.01); C08J 2381/10 (2013.01); C08J 2433/14 (2013.01); C08J 2433/22 (2013.01); C08J 2433/24 (2013.01); C08J 2477/00 (2013.01)] 37 Claims
 
1. A double network hydrogel, comprising:
(a) a first polymeric network comprising a first crosslinked zwitterionic polymer having from about 50 to about 100 mole percent zwitterionic moieties; and
(b) a second polymeric network comprising a second crosslinked zwitterionic polymer having from about 50 to about 100 mole percent zwitterionic moieties,
wherein the double network hydrogel has a compressive fracture stress of greater than about 0.9 MPa.