US 12,291,581 B2
Serpin peptides and methods of using the same
Soren Mogelsvang, Boulder, CO (US); and Cohava Gelber, Manassas, VA (US)
Assigned to SERPIN PHARMA, LLC, Manassas, VA (US)
Filed by SERPIN PHARMA, LLC, Manassas, VA (US)
Filed on Dec. 16, 2020, as Appl. No. 17/124,301.
Application 14/609,069 is a division of application No. 13/925,067, filed on Jun. 24, 2013, granted, now 8,975,224, issued on Mar. 10, 2015.
Application 17/124,301 is a continuation of application No. 16/286,298, filed on Feb. 26, 2019, granted, now 10,899,797.
Application 16/286,298 is a continuation of application No. 14/609,069, filed on Jan. 29, 2015, granted, now 10,214,562, issued on Feb. 26, 2019.
Application 13/925,067 is a continuation in part of application No. PCT/US2013/020498, filed on Jan. 7, 2013.
Claims priority of provisional application 61/699,571, filed on Sep. 11, 2012.
Claims priority of provisional application 61/584,517, filed on Jan. 9, 2012.
Prior Publication US 2021/0188912 A1, Jun. 24, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 7/08 (2006.01); A61K 38/00 (2006.01); C07K 14/81 (2006.01)
CPC C07K 7/08 (2013.01) [C07K 14/8125 (2013.01); A61K 38/00 (2013.01)] 13 Claims
 
1. A composition comprising a peptide selected from the group consisting of:
(a) a peptide consisting of the amino acid sequence X1-Z1-F-N-K-P-F-X2-Z2-X3-Z3 (SEQ ID NO: 2), wherein
X1 is V or L;
X2 is V, L or M;
X3 is M, I or V;
Z1 is any amino acid;
Z2 is a sequence of any two amino acids; and
Z3 is a sequence of any five amino acids;
(b) a peptide consisting essentially of the amino acid sequence RFNRPFLR (SEQ ID NO: 4); and
(c) a peptide consisting essentially of the amino acid sequence of RRRFNRPFLRRR (SEQ ID NO: 8).