US 12,291,579 B2
Anti-phosphocholine antibodies and methods of use thereof
Jean-Philippe Burckert, South San Francisco, CA (US); and Katherine Vousden, Saffron Walden (GB)
Assigned to Oxitope Pharma B.V., (NL)
Filed by Oxitope Pharma B.V., Naarden (NL)
Filed on Oct. 18, 2024, as Appl. No. 18/920,412.
Application 18/920,412 is a continuation of application No. PCT/IB2024/000127, filed on Mar. 18, 2024.
Claims priority of provisional application 63/452,798, filed on Mar. 17, 2023.
Prior Publication US 2025/0034283 A1, Jan. 30, 2025
Int. Cl. C07K 16/44 (2006.01); A61K 47/68 (2017.01)
CPC C07K 16/44 (2013.01) [C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01)] 20 Claims
 
1. An antibody that specifically binds phosphocholine (PC), the antibody comprising: a VH comprising the CDRH1, CDRH2, and CDRH3 amino acid sequences of the VH amino acid sequence set forth in SEQ ID NO: 27; and a VL comprising the CDRL1, CDRL2, and CDRL3 amino acid sequences of the VL amino acid sequence set forth in SEQ ID NO: 208.