US 12,291,514 B1
Ethyl 2-[9-(2-hydroxypyridin-3-yl)-3,6-diphenyl-1,8-dioxo-3,4,9,10-tetrahydroacridine-10-yl]-acetate as an antimicrobial compound
Hany Mohamed Abd El-Lateef Ahmed, Al-Ahsa (SA); Mai Mostafa Khalaf Ali, Al-Ahsa (SA); and Antar Ahmed Abdelhamid Ahmed, Sohag (EG)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Feb. 1, 2024, as Appl. No. 18/430,254.
Application 18/430,254 is a division of application No. 18/386,555, filed on Nov. 2, 2023, granted, now 11,939,315.
Int. Cl. C07D 401/04 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01)
CPC C07D 401/04 (2013.01) [A61P 31/04 (2018.01); A61P 31/10 (2018.01)] 4 Claims
 
1. A method of killing a microbe comprising contacting the microbe with a therapeutically effective amount of an ethyl 2-[9-(2-hydroxypyridin-3-yl)-3,6-diphenyl-1,8-dioxo-3,4,9,10-tetrahydroacridine-10-yl]-acetate compound; wherein the microbe is selected from the group consisting of a gram positive bacteria, one or more gram negative bacteria, a fungi, and a combination thereof; and
wherein the gram positive bacteria is Staphylococcus aureus, the one or more gram negative bacteria are selected from the group consisting of Pseudomonas aeruginosa and Escherichia coli, and a combination thereof, and the fungi is Candida albicans.