US 12,291,507 B2
Compounds and their use for the treatment of ALPHA1-antitrypsin deficiency
Nigel Ramsden, Cambridge (GB); David John Fox, Coventry Warwickshire (GB); James Andrew Huntington, Cheshire (GB); and James Michael Tomlinson, Babraham Cambridge (GB)
Assigned to CENTESSA PHARMACEUTICALS (UK) LIMITED, Altrincham (GB)
Filed by CENTESSA PHARMACEUTICALS (UK) LIMITED, Altrincham (GB)
Filed on Jun. 13, 2022, as Appl. No. 17/839,241.
Application 17/839,241 is a continuation of application No. PCT/GB2020/053194, filed on Dec. 11, 2020.
Claims priority of application No. 1918414 (GB), filed on Dec. 13, 2019.
Prior Publication US 2023/0096524 A1, Mar. 30, 2023
Int. Cl. C07D 239/54 (2006.01)
CPC C07D 239/54 (2013.01) 20 Claims
 
1. A compound represented by the structure:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt of any one thereof.