US 12,290,809 B2
Sample management module
Stefan Leo Van Workum, London (GB); Callum Robertson Smith, London (GB); Marko Dorrestijn, London (GB); and David R. Klug, London (GB)
Assigned to Panacea Diagnostics Ltd, London (GB)
Appl. No. 17/435,373
Filed by Panacea Diagnostics LTD, London (GB)
PCT Filed Feb. 28, 2020, PCT No. PCT/GB2020/050485
§ 371(c)(1), (2) Date Aug. 31, 2021,
PCT Pub. No. WO2020/178563, PCT Pub. Date Sep. 10, 2020.
Claims priority of application No. 1902792 (GB), filed on Mar. 1, 2019.
Prior Publication US 2022/0143608 A1, May 12, 2022
Int. Cl. B01L 3/00 (2006.01); A61B 10/00 (2006.01)
CPC B01L 3/502715 (2013.01) [A61B 10/0051 (2013.01); B01L 3/5023 (2013.01); A61B 2010/0006 (2013.01); B01L 2200/0684 (2013.01); B01L 2300/041 (2013.01); B01L 2300/161 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A cartridge comprising a sample management module for collecting a fluid sample, the module comprising:
a sample collection device comprising a sample collection location and a filter;
a decoupling zone configured to receive sample from the collection device;
an overflow reservoir in fluid communication with the decoupling zone to accommodate any sample that does not fit into the decoupling zone; and
an optical element comprising a surface with a plurality of capture components deposited thereon,
wherein the overflow reservoir is provided with a vent to ensure pressure within the module can be managed,
wherein the cartridge further comprises an analysis zone downstream of the sample management module and a vent hole downstream of the analysis zone,
wherein the vent hole is configured to enable air or inert gas to exit the cartridge, and
wherein the analysis zone comprises the capture component deposited surface of the optical element.